Corona Virus Lockdown Blues, Revisited & Revised

Corona Virus Lockdown Blues, Revisited & Revised

Corona Virus Lockdown Blues, Revisited & Revised

A rethink of lock down posts, and galleries
It’s been a taxing ten or so days, maintaining sanity is becoming more of a chore as this goes on. It’s taking it toll, on everyone, of that there is no doubt.
The photography has been one of the few ways of coping with the situation, and slowing the slide to previous mental health oblivion. Concentration is a real problem, this is probably why the photography helps, as it’s a bit stop start, so nothing that needs long periods concentration!

So far the images have been put on the site piecemeal, with some jumbled thoughts! So in an effort to showcase the images a bit better a set of permanent pages have been setup for the lock down photographs.

Visit the lock down galleries
 gateway page here
(Or via the site menus)

Is it over bar the accusations?

No of course not, apparently social distancing will be in place for over a year, according to the government’s scientific advisers.

As the World and government starts to consider what happens next,  the media start to talk about vaccinations, ‘contact tracing’ (mass surveillance), ending the lock down, ‘phased reopening’, half capacity social activity, temperature checks at every entrance, having to do it again for pandemic II, III, IV, V, …..  

There are more questions being asked about if the unprecedented measures taken were indeed required and if the figures and statistics being used are valid

Press conference, called by doctors Dan Erickson and Artin Massihi, to release the results of their Covid19 testing program.  Higher than expected percentage of people are infected and the vast majority show no symptoms. This is in line with other studies done at Stanford University and by Japanese scientists in China.
Dr Sarah Gangoli and Dr Bob Gill discuss the impact of COVID-19 in the UK.  The UK is set to have one of the worst COVID-19 death rates in the world.
Mike Graham speaks to journalist and author Peter Hitchens over coronavirus and the effects of lock down as he expressed concern over the long term economic damage he thought had already been done during the lock down.  Peter highlighted, that the lock down in the eyes of many people is effectively over.
Some have even questioned if the lock down will cause more problems, suffering and death, than the virus it’s self.  A valid point when you consider the effect on suicide rates proportional to a rise in unemployment, for example

Suicide rates rise about 1% for every one percentage point increase in unemployment

This statistic was reported recently in an article by Reuters, (COVID’s Other Casualties), and comes from a study carried out by the Royal College of Psychiatrists published in 2014, in The British Journal of Psychiatry
If this is applied to the UK current data, this appears to be the results:

UK Unemployment rate, for the three months December 2019 – February 2020, taken from the Office for National Statics report are:   1,364,000’s

UK Deaths by suicide in 2018, (latest figures found), from the Samaritans Suicide Stats Report 2019 are: 6859

Since the start of the lock down 1,200,000 people have made claims for Universal Credit, of which the Department of Work and Pensions have said 950,000 were successful

This represents a 69.65% increase in unemployment, applied to the 2018 numbers from the Samaritans report, potentially there will be 4732 deaths by suicide as a consequence of the measures taken to protect us.

As of the time of writing this figure is 21.83% of the total UK deaths from Corona Virus.

In addition to this the effects of people not taking exercise for an extended period, something we are constantly told we must do for the good of our health.  The effects of cancelled operations, investigations and ongoing treatments, mental health effects, and domestic abuse.

Then there is the effects on the economy, it has been reported, in the US, that some analysts predict that financial pressures would force anywhere from 20% to 50% of all small businesses to close permanently within 90 days but the reality is, it’s the same here.  In addition to this there has been a massive transfer of wealth

Was it all worth it? Was the cure worse than the disease?

Only time will tell

BAME community more at risk, a surprise to the UK Government!

In the last day or so, it has been reported that the BAME community, health workers, (quite why just health workers), are more at risk.  This has been reported as a new development that has the government and all our scientists stumped.
Quite why this would be the case, is somewhat confusing when you consider the number of studies and scientific research papers that have been released, dating back to 2005/6 on the infection routes of Corona Virus, via the ACE2 Receptor.  This research stated as part of the SARS and subsequent MERS outbreaks, both of which are Corona Virus that have caused concern in the past.

Why is this important?  Because the Asian/Eastern demographic appear to have a greater concentration of ACE2 as a number of studies over a similar timescales have suggested.

Association study of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms and essential hypertension in northern Han Chinese
Published in the Journal of Human Hypertension, in October 2006 10.1038/sj.jhh.1002090

The geographic distribution of the ACE II genotype: A novel finding
Published by Cambridge University Press, in January 2008 10.1017/S0016672307009019

A small selection ACE2 Studies

ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia
Published in the American Society for Microbiological’s Journal of Virology, in December 2005  10.1128/JVI.79.23.14614-14621.2005

Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov
Published on the bioRxiv online archive and distribution service for unpublished preprints in the life sciences, in January 2020  10.1101/2020.01.26.919985

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
Published in the International Journal of Oral Science, in February 2020  10.1038/s41368-020-0074-x

Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibility
Published in the International Journal of Oral Science, in April 2020 10.1101/2020.04.07.024752

ACE-2: The Receptor for SARS-CoV-2
R&D Systems article on potential therapies, published here

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